Caroline Tigoi is a Postdoctoral Scientist at the KEMRI–Wellcome Trust Research Programme, specializing in infectious disease surveillance, antimicrobial resistance (AMR), and microbial genomics among neonates and children in low-resource settings. She holds a DPhil in Clinical Medicine from the University of Oxford, where her research investigated the acquisition and loss of antimicrobial resistance in Gram-negative bacteria among vulnerable children.
Caroline currently serves as Principal Investigator for the NeoBAC Study in Kenya, which investigates the prevalence, aetiology, and resistance patterns of neonatal bloodstream infections. She co-leads several regional AMR initiatives, including the NIHR-funded Vaccines Against AMR study (Kenya), the EDCTP-funded SNIP Africa Trial (microbiology work package), and the SIDA-funded ALARUM One Health microbiome surveillance project on AMR across human, animal, and environmental samples. Caroline previously led laboratory activities for the Childhood Acute Illness and Nutrition (CHAIN) Network, coordinating harmonised procedures in labs across nine sites in Africa and South Asia and led the AMR sub-study.
Her work integrates surveillance, genomics, and microbiome approaches to understand colonisation and transmission dynamics, to inform infection prevention strategies such as vaccines and microbiome-based interventions to reduce AMR burden and mortality among vulnerable children.